Learn about the latest study findings from Linus Health
Visit us at booth #931, explore our sessions below, and view our AAIC posters in person on July 12 and 13 from 7:30 am to 4:15 pm local time.
Sunday, July 12
BIOMARKERS (NON-IMAGING)
Identifying Eligible Candidates For Alzheimer’s Disease-Modifying Treatment With The Digital Clock And Recall
Ali Jannati, MD, PhD
Director of Cognitive Science, Linus Health
Poster #0396
Key takeaways:
A combination of multimodal machine-learning models based on the Digital Clock and Recall (DCR) – the DCR Cognition Score and the Amyloid Positivity Risk showed strong performance for identifying individuals who have mild cognitive impairment or mild dementia likely due to Alzheimer’s disease, and therefore potentially suitable candidates for disease-modifying treatments.
DEMENTIA CARE AND HEALTH SERVICES RESEARCH
Feasibility And User Acceptance Of The Electronic Person-specific Outcome Measure (ePSOM) In Japan
Stina Saunders, PhD
Personalized Medicine Lead, Linus Health
Poster #0752
Key takeaways:
Interim data from the ePSOM feasibility study in Japan show ePSOM can be deployed in a culturally distinct clinical setting without structural adaptation, supporting its use in global AD trials to capture personally meaningful priorities and establish meaningful treatment benefits.
Monday, July 13
CLINICAL MANIFESTATIONS: NEUROPSYCHOLOGY
The Digital Clock And Recall Outperforms MOCA In Detecting Mild Cognitive Impairment In A Real-world Clinical Setting
Ali Jannati, MD, PhD
Director of Cognitive Science, Linus Health
Poster #0846
Key takeaways:
In a real-world clinical sample, Linus Health’s Digital Clock and Recall outperformed the MoCA in detecting mild cognitive impairment against clinical diagnosis. The DCR Cognition Score demonstrated higher diagnostic accuracy and substantially greater specificity, thereby reducing false-positive classifications while maintaining comparable sensitivity. DCR also identified individuals with impairment that MoCA missed, supporting this machine learning-enabled digital assessment as a tool to improve early detection and diagnostic confidence in routine clinical care.
Curious about our solutions for clinical trials?
Take a closer look at our platform to learn more about the suite of digital assessments Linus offers.